Lipstick tattoo Lipstick tattoo is one of the most common beauty methods among women that should be done by relevant experts in this field with high accuracy and skill. Your beauty care provider will already put an anesthetic on your lips to create a lipstick tattoo and help minimize pain and discomfort. The less you tolerate the pain, the more uncomfortable you will feel. However, some people may not have much pain at all. You may want to consider taking acetaminophen before your appointment to reduce the chance of feeling pain.